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Audit of coroners and cemeteries sought to establish number of unidentified…

first_imgWATCH: “Everyone is fighting so hard to get on” – Pat Ryan on competitive camogie squads Email Billy Lee names strong Limerick side to take on Wicklow in crucial Division 3 clash TAGSKeeping Limerick PostedlimerickLimerick Post Linkedin Roisin Upton excited by “hockey talent coming through” in Limerick RELATED ARTICLESMORE FROM AUTHOR Advertisement Previous articleWATCH: Cian Lynch shows off his skills to promote Team Limerick Clean UpNext articleTom Savage: Good clubs are built on the work and character of men like Billy Holland David Raleigh WhatsAppcenter_img Limerick Ladies National Football League opener to be streamed live A LABOUR TD has called on the Minister for Justice to appoint an agency to carry out a national audit of coroners and cemeteries to establish the number of unidentified bodies in the State, in order to try to help families of missing persons perhaps find their missing loved ones.The call, by Deputy Duncan Smith, comes exactly a month after gardai informed the family of Limerick man Denis Walsh – who was declared missing for 25 years – that his unidentified remains had actually been found four weeks after he went missing on March 9th, 1996.Sign up for the weekly Limerick Post newsletter Sign Up It also emerged Mr Walsh’s remains were held in storage at the Mortuary at University Hospital Galway for 18 years, before being laid to rest at a Galway County Council communal graveyard in Bohermore, in 2014.Gardai were notified on February 5th last, that because of advances in DNA profiling, it could be confirmed that human remains found on the shore at Inis Mor, on April 7, 1996, were that of Mr Walsh.Denis Walsh’s family continue to ask questions as to how his body was not identified sooner, and why they had not been informed at the time of an unidentified partial body being found.Mr Walsh’s parents said they dropped flyers with Denis’s photograph into Garda stations in Galway the day before discovery of remains on Inis Mor.The couple returned to Galway a month later to drop more flyers around Galway, a day before gardai appealed for information on RTE Crimeline about the discovery of their son’s unidentified remains.“There was no connection made, as far as we can see,” Denis Walsh’s brother, Paul, told this reporter last month.“How come the gardaí at the time did not join up the dots sooner? Did no garda in Galway check what people were reported missing around that time, and was no garda in Limerick aware of a body being found in Galway? I’m not satisfied,” added the deceased’s heartbroken Denis Walsh snr.The family have sought permission to exhume Mr Walsh’s remains and lay him to rest finally in his native Limerick.Many other families of missing persons have now been left pondering whether their missing loved one’s remains have been buried or are they still be held in storage.In a statement today, Deputy Duncan Smith said: “In Ireland, there are 823 missing persons files open. However, there is no record of how many remains have been interred in cemeteries, or remain in morgues, as the current rules regulating coroners does not compel them to report unidentified remains to a central system.““There is no one individual or authority with responsibility for collating all the unidentified remains that have been found in this country. We literally do not know how many unidentified remains have been interred in cemeteries or remain in morgues as rules regulating coroners does not compel them to report unidentified remains to a central repository.”“This is set against a total of 823 current missing persons files currently open, the oldest dating back to 1951.“Deputy Smith said coroners “are not compelled“ to report how many unidentified bodies are in the country, “which has led to the perverse situation where families of missing persons must go to individual coroners’ and graveyards to seek information relating to their loved one”.“One family described this process as like going to 40 lost and found desks. At a time of horrendous heartbreak, it’s simply unacceptable that families of missing persons would be treated this way by the State,” he said.“I am calling on the Minister for Justice to right this wrong for families. If coroners cannot find out the ‘how’, they certainly don’t have to find out the who.”“The Corners must be compelled to keep records of unidentified bodies, identifying the cause of their death and opening a system that would reunite the remains of these people with their family and loved ones.““The media has gone above the call of duty for many of these families, searching for answers to these harrowing stories of loss. Instead of having families turn to journalists and the media to solve the mystery of missing persons, the State must play an active role in trying to solve these cases and bring truth to families after the headlines have moved on.” Donal Ryan names Limerick Ladies Football team for League opener Twitter Facebook LimerickNewsAudit of coroners and cemeteries sought to establish number of unidentified remains, in order to help bring closure for families of missing personsBy David Raleigh – March 6, 2021 107 Print Limerick’s National Camogie League double header to be streamed live last_img read more

Engineered mini-kidneys come of age

first_img The first fully 3-D-printed heart-on-a-chip A glomerulus-on-a-chip could model patient-specific kidney diseases, guide therapeutic discovery Human stem cells model the kidney’s filtration barrier With organs-in-a-dish a growing success story, research with organoids has increasingly proved its worth. Already, scientists can create organoids that have many of the cell types and complex architectures of human organs such as the kidney, liver, guts, and even the brain.Most organoids grown in vitro , however, have lacked the vasculature to provide the cells with oxygen and nutrients, remove metabolic waste, and facilitate communication between cell types — functions that drive their maturation into working tissue-building blocks.When it comes to kidney organoids, that shortcoming has kept researchers from reproducing key functions, such as blood filtration, reabsorption, and urine production. A vascularized organoid could better model kidney diseases, enhance renal drug toxicity testing, and ultimately lead to building blocks for replacement therapies.To answer that need, a team of researchers from the Wyss Institute for Biologically Inspired Engineering, the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS), Brigham and Women’s Hospital, and the Harvard Stem Cell Institute has developed a powerful new approach as part of the Wyss’ new 3D Organ Engineering initiative. By exposing stem cell-derived organoids to fluidic shear stress, they have significantly expanded their vascular networks and improved the maturation of kidney compartments. The work is published in Nature Methods.,The improvements are a next step on a path begun in 2015, when Ryuji Morizane and Joseph Bonventre developed a way to make kidney organoids from human pluripotent stem cells. But while their organoids had well-organized nephrons, which filter the blood, and primitive blood vessels,  “they still lacked pervasive vascular compartments with perfusable lumens,” said Morizane, an assistant professor at Brigham and Women’s Hospital and Harvard Medical School (HMS), a member of the Harvard Stem Cell Institute, and, with co-author Jennifer Lewis, co-leader of the research team.To develop these, the team used the Lewis lab’s strategies to create vascularized human tissues, including 3-D kidney-on-chip models, using perfusable and durable 3-D bioprinting. They hypothesized that fluid flow could help the chip models form blood vessels from precursor endothelial cells found in growing kidney organoids — and successfully, for the first time, demonstrated that by exposing the organoids to fluid flow, their vascularization and maturation can be enhanced in vitro, rather than in an animal host, said Morizane.A developing glomerulus in a kidney organoid cultured under flow showing invasion by a single capillary, which is an important step in nephron development. Credit: Wyss Institute at Harvard University“We determined the right combination of underlying extracellular matrix, media additives, and fluidic shear stress under which human stem-cell derived organoids would flourish when grown in our 3-D-printed millifluidic chips,” said Kimberly Homan, a research associate in Lewis’ group and, with Navin Gupta, first author on the study.“The vascular networks form close to the epithelial structures that build the glomerular and tubular compartments, and in turn promote epithelial maturation. This integrated process works really like a two-way street,” said Gupta, a clinical research fellow in Morizane’s lab.“This important advance opens up new avenues for accurately testing drug toxicity in vitro … and modeling kidney diseases, like polycystic kidney disease, that affect specific structures and cell types using patient-derived stem cells as the starting point,” said Lewis, who is a core faculty member of the Wyss Institute and co-leader of its 3D Organ Engineering Initiative. Lewis is also the Hansjörg Wyss Professor of Biologically Inspired Engineering at SEAS and a member of the Harvard Stem Cell Institute.“Our method may pave the way to also vascularize other types of organoids, such as the liver organoids,” she said.“This study is a great example of the importance of mechanobiology and the potential power of the Wyss Institute’s 3D Organ Engineering Initiative. It provides an important cornerstone for many efforts that aim to create functional human tissues de novo for research, pharmaceutical, and tissue regenerative applications,” said Wyss Institute Founding Director Donald Ingber, who is also the Judah Folkman Professor of Vascular Biology at HMS and the Vascular Biology Program at Boston Children’s Hospital, as well as professor of bioengineering at SEAS.Other authors on the study are Bonventre, the Samel A. Levine Professor of Medicine at HMS, chief of renal medicine at the Brigham, and a member of the Harvard Stem Cell Institute; past and present members of Lewis’ team, including Katharina Kroll, Mark Skylar-Scott, David Kolesky, Donald Mau, and Thomas Ferrante; Tomoya Miyoshi on Morizane’s team; and M. Todd Valerius, principle investigator at the Brigham.The study was funded by the National Institutes of Health, Harvard’s Wyss Institute for Biologically Inspired Engineering, and the Harvard Stem Cell Institute. Wyss Institute’s goal is to improve America’s ability to respond to nuclear radiation incidentscenter_img Related Organs-on-chips evaluate therapies for lethal radiation exposure Technique paves the way for more complex, customizable devices last_img read more

Support local businesses through the Community Tee Project

first_imgParker is donating Salon Trend’s share of the proceeds to the non-profit, New York Bully Crew. “I didn’t think anyone was going to buy a shirt. Then it turned into one, 10, 20, 30, and I think we’re over 70 or 80 at this point,” said Parker. “Here’s an opportunity for them to get back out in front of people, have people support them, buying a t-shirt, being able to wear their logo and help these companies out,” said Worldwide Sport Supply owner TJ Ciaravino. “Literally, the next day we made the complete switch to virtual because we knew consistency was really important to our squad,” said owner Marysol Burgos. The shirts cost $19. If you would like to purchase a shirt from the Community Tee Project, click here. “Rent has to be paid, we have to keep the lights on, we appreciate having heat when we’re here teaching so all of those things were real concerns about how are we going to cover the cost of a small business when we are shut down,” said owner Jenna Moore. Salon Trend got involved with the project early on. The store has partnered with more than 100 businesses to sell shirts with their logo on them. That’s why when they heard about the Community Tee Project, JAM jumped on board. “It just gave us such a boost of morale, coming down the home stretch, I pray,” said Salon Trend owner Sherette Parker. While the project has been able to help financially, it’s also giving some local businesses energy. Atlya Studio in Endwell is also choosing to donate its portion of the sales to the non-profit, Mom’s House.center_img “I had to lay my staff off a month ago and we’re just now able to get them back to work,” said Ciaravino. (WBNG) — Businesses around the Southern Tier have taken a hit due to the pandemic. While it is offering online classes, JAM still has bills to pay. $10 goes back directly to the featured business while the other $9 goes to Worldwide Sport Supply. While some are set to reopen Friday, businesses like gyms and salons are waiting to open their doors. JAM Fitness in Vestal is a studio that offers group workout classes, and has been closed for weeks now. “I’ve had a lot of people and customers and guests reach out to me and just show their concern about our business being closed. I feel like it’s sort of a situation of pay it forward,” said owner Danielle Loeb. While the Community Tee Project was meant to help local businesses, it’s reaching even further, bringing the whole Southern Tier together. The Community Tee Project was brought to the area by Worldwide Sport Supply in Vestal. If you are interested in getting your business involved to partner with the Community Tee Project, email TJ Ciaravino at [email protected] The online store closes June 1.last_img read more

Miami-Dade Mayor’s Protective Message: Assume Everyone Has Coronavirus

first_imgGimenez added the approach is similar to what Florida Gov. Ron DeSantis has done with the state’s EOC.The mayor also emphasized that residents should be taking the proper measures, which include keeping social distancing, constantly washing hands and avoiding touching one’s face.“The 2.8 million residents that live in in Miami-Dade need to assume that everybody that they’re in contact with is infected,” he says. “If you do that, you’ll take measures that will protect yourself and will protect others. That’s the way we beat this virus.” Miami-Dade County Mayor Carlos Gimenez is currently in self-quarantine at his home due to the outbreak of coronavirus.Although a test he took last week came back negative, the mayor noted that sometimes symptoms can take longer to show up and out of an abundance of caution, he decided not to interact with others and to spreading the virus.On Saturday night, Gimenez tweeted that the Miami-Dade Emergency Management will begin operating at a Level II due to the ongoing concerns over the threat of COVID-19.“It’s an activation of our EOC (Emergency Operations Center),” Gimenez explained during an appearance on Miami television station WPLG. “That means it’s open 24 hours a day, so that if anything happens, we will have somebody there.”last_img read more